PT - JOURNAL ARTICLE AU - Hans Balink AU - Evelien Hut AU - Thomas Pol AU - Freerk-Jan Flokstra AU - Mark Roef TI - Suppression of <sup>18</sup>F-FDG Myocardial Uptake Using a Fat-Allowed, Carbohydrate-Restricted Diet AID - 10.2967/jnmt.110.076489 DP - 2011 Sep 01 TA - Journal of Nuclear Medicine Technology PG - 185--189 VI - 39 IP - 3 4099 - http://tech.snmjournals.org/content/39/3/185.short 4100 - http://tech.snmjournals.org/content/39/3/185.full SO - J. Nucl. Med. Technol.2011 Sep 01; 39 AB - Patients prepared by the generally used fasting protocol show variable myocardial 18F-FDG uptake, which may result in difficult interpretation of mediastinal 18F-FDG uptake. This retrospective study described the effect of a 1-d fat-allowed, carbohydrate-restricted diet on myocardial 18F-FDG uptake. Methods: The study included 100 patients on a carbohydrate-restricted diet from the Medical Center Leeuwarden and 100 patients on an unrestricted diet from the University Medical Center of Utrecht. A visual uptake scale was used, with category 0 indicating myocardial uptake less than liver uptake, category 1 indicating myocardial uptake comparable to liver uptake, and category 2 indicating myocardial uptake considerably higher than liver uptake. Results: After a carbohydrate-restricted diet, 68% of patients had a homogeneously low myocardial uptake of 18F-FDG (category 0), 14% had moderate myocardial uptake (category 1), and 18% had homogeneously intense myocardial uptake (category 2). Without a carbohydrate-restricted diet, 69% of patients showed a homogeneously intense myocardial uptake (category 2), 16% a moderate myocardial uptake (category 1), and 15% a homogeneously low myocardial uptake (category 0). Conclusion: A fat-allowed, carbohydrate-restricted diet starting the day before 18F-FDG administration suppresses myocardial 18F-FDG uptake satisfactorily.