RT Journal Article SR Electronic T1 Understanding the Cause of an Unreadable Nuclear Medicine Image: A Case of Unexpected Results with 123I Whole-Body Scintigraphy JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP jnmt.113.136523 DO 10.2967/jnmt.113.136523 A1 Skweres, Justin A1 Yang, Zhiyun A1 Gonzalez-Toledo, Eduardo YR 2014 UL http://tech.snmjournals.org/content/early/2014/08/26/jnmt.113.136523.abstract AB When unexpected results are obtained with standard image collection, the nuclear medicine physician must consider many technical factors that may have contributed. When image quality is poor, prior radiotracer administration, among other things, should always be considered. Our case demonstrates how knowledge of patient history and basic principles of nuclear medicine physics allows recognition of the septal penetration artifact. This allows the nuclear medicine physician to tailor the exam to an individual patient and obtain the most useful diagnostic information for the clinician.