RT Journal Article
SR Electronic
T1 Quantitative salivary gland scintigraphy.
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 20
OP 26
VO 27
IS 1
A1 S Klutmann
A1 K H Bohuslavizki
A1 S Kröger
A1 C Bleckmann
A1 W Brenner
A1 J Mester
A1 M Clausen
YR 1999
UL http://tech.snmjournals.org/content/27/1/20.abstract
AB Uptake of 99mTc-pertechnetate in salivary glands reflects intact salivary gland parenchyma. However, no standardized protocol for an accurate quantification of parenchymal function has been established so far.In this paper we report on a validated acquisition protocol supplying a normal database for standardized quantitative salivary gland scintigraphy.The major advantage of salivary gland scintigraphy, as compared to other imaging modalities, is that both parenchymal function and excretion fraction of all four major salivary glands (i.e., parotid and submandibular glands) can be simultaneously quantified with a single intravenous injection.Quantitative salivary gland scintigraphy is demonstrated to be a suitable imaging modality for research applications in evaluating the effects of radioprotective drugs on salivary glands. Salivary gland scintigraphy is easy to perform, reproducible and well-tolerated by the patient.