PT  - JOURNAL ARTICLE
AU  - S Klutmann
AU  - K H Bohuslavizki
AU  - S Kröger
AU  - C Bleckmann
AU  - W Brenner
AU  - J Mester
AU  - M Clausen
TI  - Quantitative salivary gland scintigraphy.
DP  - 1999 Mar 01
TA  - Journal of Nuclear Medicine Technology
PG  - 20--26
VI  - 27
IP  - 1
4099  - http://tech.snmjournals.org/content/27/1/20.short
4100  - http://tech.snmjournals.org/content/27/1/20.full
SO  - J. Nucl. Med. Technol.1999 Mar 01; 27
AB  - Uptake of 99mTc-pertechnetate in salivary glands reflects intact salivary gland parenchyma. However, no standardized protocol for an accurate quantification of parenchymal function has been established so far.In this paper we report on a validated acquisition protocol supplying a normal database for standardized quantitative salivary gland scintigraphy.The major advantage of salivary gland scintigraphy, as compared to other imaging modalities, is that both parenchymal function and excretion fraction of all four major salivary glands (i.e., parotid and submandibular glands) can be simultaneously quantified with a single intravenous injection.Quantitative salivary gland scintigraphy is demonstrated to be a suitable imaging modality for research applications in evaluating the effects of radioprotective drugs on salivary glands. Salivary gland scintigraphy is easy to perform, reproducible and well-tolerated by the patient.