RT Journal Article
SR Electronic
T1 Dual-Isotope Protocol for Indium-111 Capromab Pendetide Monoclonal Antibody Imaging
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 174
OP 177
VO 26
IS 3
A1 Nellie L. Kelty
A1 Lawrence E. Holder
A1 Salma H. Khan
YR 1998
UL http://tech.snmjournals.org/content/26/3/174.abstract
AB Objective: A dual-isotope imaging protocol using 99mTc-labeled red blood cells with 111In capromab pendetide monoclonal antibody imaging for detecting and localizing nodal metastasis in prostate cancer is described. Methods: This protocol involves a single SPECT acquisition that is less time consuming and more comfortable for the patient than the currently recommended method, which requires two separate SPECT acquisitions performed on different days. Results: Forty patients were studied with the dual-isotope protocol. Preliminary data suggest increased accuracy compared with the single-isotope technique. Conclusion: The dual-isotope technique assures the precise image registration needed for accurate comparison of blood pool and pelvic lymph node activity that is required for confident and accurate image interpretation.