PT  - JOURNAL ARTICLE
AU  - Nellie L. Kelty
AU  - Lawrence E. Holder
AU  - Salma H. Khan
TI  - Dual-Isotope Protocol for Indium-111 Capromab Pendetide Monoclonal Antibody Imaging
DP  - 1998 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 174--177
VI  - 26
IP  - 3
4099  - http://tech.snmjournals.org/content/26/3/174.short
4100  - http://tech.snmjournals.org/content/26/3/174.full
SO  - J. Nucl. Med. Technol.1998 Sep 01; 26
AB  - Objective: A dual-isotope imaging protocol using 99mTc-labeled red blood cells with 111In capromab pendetide monoclonal antibody imaging for detecting and localizing nodal metastasis in prostate cancer is described. Methods: This protocol involves a single SPECT acquisition that is less time consuming and more comfortable for the patient than the currently recommended method, which requires two separate SPECT acquisitions performed on different days. Results: Forty patients were studied with the dual-isotope protocol. Preliminary data suggest increased accuracy compared with the single-isotope technique. Conclusion: The dual-isotope technique assures the precise image registration needed for accurate comparison of blood pool and pelvic lymph node activity that is required for confident and accurate image interpretation.