RT Journal Article SR Electronic T1 Reducing Exposure from 57Co Sources During Breast Lymphoscintigraphy by Optimizing Energy Windows and Other Suggested Enhancements of Acquisition and the Display of Images JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 198 OP 205 VO 32 IS 4 A1 Krynyckyi, Borys R. A1 Sata, Suzana A1 Zolty, Ian A1 Kim, Chun K. A1 Knešaurek, Karin YR 2004 UL http://tech.snmjournals.org/content/32/4/198.abstract AB We set out to measure the reduction in exposure attained by using a weak 57Co sheet source with optimal energy windows. Methods: Two groups of 10 lymphoscintigraphy studies were analyzed. Group 1 consisted of 10 studies obtained with a stronger source of 57Co, 59 MBq (1.6 mCi) at the time of data acquisition, with transmission images acquired at 3 energy windows of 115–129, 130–134, and 135–150 keV. Group 2 consisted of 10 studies with a weaker sheet source of 57Co, 11 MBq (0.3 mCi). Transmission images were acquired at 3 energy windows of 112–132, 130–134, and 135–150 keV. Same-sized regions of interest (ROIs) were drawn on the patient’s torso (PT) and on the nonattenuated image of the transmission source itself (TS), all 1-min images. The counts in each ROI obtained over 1 min and the ratios between the TS ROI and the PT ROI were calculated for all of the energies. Dosimetry calculations based on measured exposure rates and the activity of the sheet sources were used to calculate the patient equivalent dose at 30 cm. Results: For the 57Co energy window, group 1 had an average ROI count of 1,955 in the TS region and 135 counts in the PT region. The average ratio of TS/PT was 15.4. Similarly, group 2 had an average ROI count of 646.4 in the TS region and 91.2 counts in the PT region. The average ratio of TS/PT was 8.6. The relative “outlining performance,” when comparing the 57Co and 99mTc windows, showed an average improvement when using the 57Co window of 4.4 and 5.8 times for group 1 and group 2, respectively (TS/PT at 57Co window)/(TS/PT at 99mTc window). Estimates of the patient equivalent dose per study were 2.30 μSv for the stronger 57Co flood source and 0.46 μSv for the weaker 57Co flood source, a 5-fold reduction in equivalent dose. Technologists received less than half of the above doses. Conclusion: Use of expanded, separate energy windows optimized for the primary 122-keV photon of 57Co greatly improves transmission scan image quality compared with the standard 140-keV 99mTc windows used for the delineation of the sentinel node. This markedly reduces exposure for all, by allowing the use of a weaker source, and can save time.