TY - JOUR T1 - Severe Systemic Reaction to <sup>99m</sup>Tc-Methylene Diphosphonate: A Case Report JF - Journal of Nuclear Medicine Technology JO - J. Nucl. Med. Technol. SP - 76 LP - 78 VL - 31 IS - 2 AU - Kottekkattu K. Balan AU - Arabinda K. Choudhary AU - Anupama Balan AU - Gordon Wishart Y1 - 2003/06/01 UR - http://tech.snmjournals.org/content/31/2/76.abstract N2 - We report an unusual severe systemic reaction that occurred in a woman after a 99mTc-methylene diphosphonate bone scan and for which no alternative explanation could be found. The bone scintigram showed diffusely increased uptake in the liver and kidneys accompanied by reversible dysfunction of these organs and dermatologic manifestations. We speculate that an immune-mediated mechanism may have caused this unusual reaction. ER -