PT - JOURNAL ARTICLE AU - Kıratlı, Pınar Özgen AU - Volkan Salancı, Bilge TI - Testing Different Storage Conditions for <sup>99m</sup>Tc-MAG3 Kit: Can Hot Fractioning Reduce the Cost per Unit Dose? DP - 2003 Jun 01 TA - Journal of Nuclear Medicine Technology PG - 74--75 VI - 31 IP - 2 4099 - http://tech.snmjournals.org/content/31/2/74.short 4100 - http://tech.snmjournals.org/content/31/2/74.full SO - J. Nucl. Med. Technol.2003 Jun 01; 31 AB - Since its release for routine clinical use, 99mTc-mercaptoacetyltriglycine (MAG3) has become an important alternative to 131I-labeled orthoiodohippuran. The cold kit for MAG3 is expensive, especially in developing countries. Therefore, unique storage conditions should be provided for cost reduction. Cold fractioning is a well-known procedure but has special requirements, such as a nitrogen tank and a laminar flow hood. The aim of this study was to prolong the shelf life of 99mTc-labeled MAG3 by a hot fractioning method, which separates the patient doses after 99mTc labeling. The radiochemical purity of the 99mTc-labeled MAG3 kit was tested under different storage conditions. Hot fractioning of the 99mTc-labeled MAG3 kit was found to be a possible alternative to cold fractioning for routine clinical studies.