RT Journal Article SR Electronic T1 Clinical and Technical Considerations for Brain PET Imaging for Dementia JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 5 OP 8 DO 10.2967/jnmt.118.220087 VO 48 IS 1 A1 Acuff, Shelley N. A1 Mathotaarachchi, Sulantha A1 Zukotynski, Katherine A1 Osborne, Dustin A1 Subramaniam, Rathan YR 2020 UL http://tech.snmjournals.org/content/48/1/5.abstract AB The number of cases of dementia has dramatically increased over the last decade. Imaging of the brain with PET has been used for many years, but in the past decade the radiopharmaceuticals and technology available for imaging dementia have vastly improved. In recent years, the U.S. Food and Drug Administration has approved 3 PET radiopharmaceuticals for detecting amyloid in brain, and tau PET radiopharmaceuticals are being investigated in clinical trials for use in dementia imaging. This paper will discuss different forms of dementia that can be imaged with PET, review common radiopharmaceuticals used for imaging dementia, and provide technical recommendations for performing the studies.