PT - JOURNAL ARTICLE AU - Acuff, Shelley N. AU - Mathotaarachchi, Sulantha AU - Zukotynski, Katherine AU - Osborne, Dustin AU - Subramaniam, Rathan TI - Clinical and Technical Considerations for Brain PET Imaging for Dementia AID - 10.2967/jnmt.118.220087 DP - 2020 Mar 01 TA - Journal of Nuclear Medicine Technology PG - 5--8 VI - 48 IP - 1 4099 - http://tech.snmjournals.org/content/48/1/5.short 4100 - http://tech.snmjournals.org/content/48/1/5.full SO - J. Nucl. Med. Technol.2020 Mar 01; 48 AB - The number of cases of dementia has dramatically increased over the last decade. Imaging of the brain with PET has been used for many years, but in the past decade the radiopharmaceuticals and technology available for imaging dementia have vastly improved. In recent years, the U.S. Food and Drug Administration has approved 3 PET radiopharmaceuticals for detecting amyloid in brain, and tau PET radiopharmaceuticals are being investigated in clinical trials for use in dementia imaging. This paper will discuss different forms of dementia that can be imaged with PET, review common radiopharmaceuticals used for imaging dementia, and provide technical recommendations for performing the studies.