PT - JOURNAL ARTICLE AU - Harvey A. Ziessman TI - Sincalide: A Review of Clinical Utility, Proper Infusion Methodology, and Alternative Cholecystogogues AID - 10.2967/jnmt.119.226019 DP - 2019 Sep 01 TA - Journal of Nuclear Medicine Technology PG - 210--212 VI - 47 IP - 3 4099 - http://tech.snmjournals.org/content/47/3/210.short 4100 - http://tech.snmjournals.org/content/47/3/210.full SO - J. Nucl. Med. Technol.2019 Sep 01; 47 AB - Sincalide (Kinevac) is widely used in conjunction with cholescintigraphy for a variety of clinical indications. Over the years, numerous publications have verified the optimal infusion methodology. Published data and consensus recommendations emphasize that sincalide, 0.02 μg/kg, should be infused over 60 min. Production problems sometimes limit the availability of sincalide. In that case, non–Food and Drug Administration pharmacy-compounded sincalide may serve as an alternative. Fatty meals have also been used. Various illnesses and drugs may inhibit gallbladder contraction. Thus, these drugs should be withheld for 48 h before the study. Sincalide cholescintigraphy is most commonly used to diagnose or exclude chronic acalculous gallbladder disease. The study should preferably be performed as an outpatient procedure.