PT  - JOURNAL ARTICLE
AU  - Alonso, Omar
AU  - Martínez, Miguel
AU  - Lago, Graciela
AU  - Espasandin, José
TI  - Preoperative Evaluation of Sentinel Lymph Node Status in Melanoma by Means of <sup>99m</sup>Tc-MIBI and Lymphoscintigraphy: A Case Report
DP  - 2001 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 152--153
VI  - 29
IP  - 3
4099  - http://tech.snmjournals.org/content/29/3/152.short
4100  - http://tech.snmjournals.org/content/29/3/152.full
SO  - J. Nucl. Med. Technol.2001 Sep 01; 29
AB  - Previous reports have shown that 99mTc-sestamibi (MIBI) could detect clinically occult metastatic melanoma lesions. This article reports on a patient with invasive melanoma of the right heel in whom the sentinel node status was preoperatively evaluated with this tracer. Although regional lymph nodes were clinically negative, 99mTc-MIBI scintigraphy showed focal increased tracer uptake in the right groin that corresponded to the location of 2 sentinel nodes visualized by lymphoscintigraphy with 99mTc-colloidal rhenium sulfide performed the same day. A γ-probe was used intraoperatively to guide the excision of the sentinel nodes that were further classified as metastatic by histopathology. This double-technique approach is technically feasible and has the potential of selecting a group of patients who might benefit from a selective complete lymphadenectomy.