RT Journal Article
SR Electronic
T1 Small Cell Transformation of Metastatic Prostate Adenocarcinoma Diagnosed by Dual-Tracer PET/CT (<sup>68</sup>Ga-PSMA and <sup>18</sup>F-FDG): Potential Clinical Utility in Therapeutic Decision Making and Treatment Monitoring
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 85
OP 87
DO 10.2967/jnmt.118.215582
VO 47
IS 1
A1 Rahul Parghane
A1 Sandip Basu
YR 2019
UL http://tech.snmjournals.org/content/47/1/85.abstract
AB Transformed small cell carcinoma of the prostate represents a tumor biology distinct from its adenocarcinoma counterpart, and penile metastasis from prostate cancer is a rare phenomenon. Biologic heterogeneity among metastatic lesions in a patient with prostatic adenocarcinoma with SCPCa transformation is presented here. The case report shows the significance of using dual-tracer PET/CT with 68Ga-prostate-specific membrane antigen and 18F-FDG in diagnosing small cell carcinoma of prostate transformation in certain lesions, thereby guiding therapeutic strategies. Furthermore, the value of sequential dual-tracer PET/CT in assessing overall disease status, theranostics, and response to multimodality therapy is illustrated.