PT  - JOURNAL ARTICLE
AU  - Rahul Parghane
AU  - Sandip Basu
TI  - Small Cell Transformation of Metastatic Prostate Adenocarcinoma Diagnosed by Dual-Tracer PET/CT (<sup>68</sup>Ga-PSMA and <sup>18</sup>F-FDG): Potential Clinical Utility in Therapeutic Decision Making and Treatment Monitoring
AID  - 10.2967/jnmt.118.215582
DP  - 2019 Mar 01
TA  - Journal of Nuclear Medicine Technology
PG  - 85--87
VI  - 47
IP  - 1
4099  - http://tech.snmjournals.org/content/47/1/85.short
4100  - http://tech.snmjournals.org/content/47/1/85.full
SO  - J. Nucl. Med. Technol.2019 Mar 01; 47
AB  - Transformed small cell carcinoma of the prostate represents a tumor biology distinct from its adenocarcinoma counterpart, and penile metastasis from prostate cancer is a rare phenomenon. Biologic heterogeneity among metastatic lesions in a patient with prostatic adenocarcinoma with SCPCa transformation is presented here. The case report shows the significance of using dual-tracer PET/CT with 68Ga-prostate-specific membrane antigen and 18F-FDG in diagnosing small cell carcinoma of prostate transformation in certain lesions, thereby guiding therapeutic strategies. Furthermore, the value of sequential dual-tracer PET/CT in assessing overall disease status, theranostics, and response to multimodality therapy is illustrated.