@article {Parghane85, author = {Rahul Parghane and Sandip Basu}, title = {Small Cell Transformation of Metastatic Prostate Adenocarcinoma Diagnosed by Dual-Tracer PET/CT (68Ga-PSMA and 18F-FDG): Potential Clinical Utility in Therapeutic Decision Making and Treatment Monitoring}, volume = {47}, number = {1}, pages = {85--87}, year = {2019}, doi = {10.2967/jnmt.118.215582}, publisher = {Society of Nuclear Medicine}, abstract = {Transformed small cell carcinoma of the prostate represents a tumor biology distinct from its adenocarcinoma counterpart, and penile metastasis from prostate cancer is a rare phenomenon. Biologic heterogeneity among metastatic lesions in a patient with prostatic adenocarcinoma with SCPCa transformation is presented here. The case report shows the significance of using dual-tracer PET/CT with 68Ga-prostate-specific membrane antigen and 18F-FDG in diagnosing small cell carcinoma of prostate transformation in certain lesions, thereby guiding therapeutic strategies. Furthermore, the value of sequential dual-tracer PET/CT in assessing overall disease status, theranostics, and response to multimodality therapy is illustrated.}, issn = {0091-4916}, URL = {https://tech.snmjournals.org/content/47/1/85}, eprint = {https://tech.snmjournals.org/content/47/1/85.full.pdf}, journal = {Journal of Nuclear Medicine Technology} }