RT Journal Article
SR Electronic
T1 Can <sup>68</sup>Ga-DOTA Peptides Be Potential Radiotracers for PET Imaging of the Spleen?
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 133
OP 135
DO 10.2967/jnmt.117.203448
VO 46
IS 2
A1 Ismet Sarikaya
A1 Abdelhamid H. Elgazzar
A1 Ali Sarikaya
A1 Naheel Alnafisi
A1 Saud Alenezi
YR 2018
UL http://tech.snmjournals.org/content/46/2/133.abstract
AB On radionuclide somatostatin receptor imaging studies, the spleen shows high physiologic uptake. Reducing the intensity of the image settings helps to better assess the distribution of radiotracer in the spleen. In our routine studies, we incidentally recognized that 68Ga-DOTANOC PET provides higher-resolution splenic images than 111In-octreotide SPECT. Autoradiography and immunohistochemistry studies have shown that somatostatin receptors are located mainly in the red pulp of the spleen. The distribution of 68Ga-DOTANOC in the spleen appears to correlate with the distribution of red pulp. In this article, we present 68Ga-DOTANOC PET/CT spleen images of our patients.