PT - JOURNAL ARTICLE AU - Mathieu Charest AU - Josephine Pressacco AU - Jaramie Thomas-Gittens TI - Malignant Peripheral Nerve Sheath Tumors of the Pericardium in a Patient with Neurofibromatosis Type 1: The Diagnostic Value of <sup>18</sup>F-FDG PET/CT and <sup>123</sup>I-MIBG SPECT/CT AID - 10.2967/jnmt.117.199927 DP - 2018 Mar 01 TA - Journal of Nuclear Medicine Technology PG - 61--62 VI - 46 IP - 1 4099 - http://tech.snmjournals.org/content/46/1/61.short 4100 - http://tech.snmjournals.org/content/46/1/61.full SO - J. Nucl. Med. Technol.2018 Mar 01; 46 AB - A 25-y-old woman with known neurofibromatosis type 1 and a large anterior mediastinal mass was investigated. 18F-FDG PET/CT revealed a radiotracer-avid anterior mediastinal mass having an SUVmax of 4.3 and demonstrating a hypoactive center. The 123I-metaiodobenzylguanidine SPECT/CT study performed subsequently did not demonstrate any uptake, thereby excluding, for the most part, the diagnosis of paraganglioma or neuroblastoma. At final pathology, a malignant peripheral nerve sheath tumor of the pericardium with areas of chondrosarcomatous and angiosarcomatous differentiation was diagnosed.