PT - JOURNAL ARTICLE AU - Sadiye Altun Tuzcu AU - Zafer Pekkolay AU - Faruk Kılınç AU - Alpaslan Kemal Tuzcu TI - <sup>68</sup>Ga-DOTATATE PET/CT Can Be an Alternative Imaging Method in Insulinoma Patients AID - 10.2967/jnmt.117.192708 DP - 2017 Sep 01 TA - Journal of Nuclear Medicine Technology PG - 198--200 VI - 45 IP - 3 4099 - http://tech.snmjournals.org/content/45/3/198.short 4100 - http://tech.snmjournals.org/content/45/3/198.full SO - J. Nucl. Med. Technol.2017 Sep 01; 45 AB - Insulinomas are the most common cause of hypoglycemia, resulting from endogenous hyperinsulinism. The diagnosis of insulinoma is established by demonstrating inappropriately high serum insulin concentrations during a spontaneous or induced episode of hypoglycemia. Most insulinomas are islet-cell tumors. They are often small (&lt;2 cm), benign, and difficult to localize with current imaging techniques. Insulinomas can be detected using either noninvasive procedures (e.g., transabdominal ultrasonography, spiral CT, MRI, 111In-pentetreotide imaging, and 18F-l-dihydroxyphenylalanine PET) or invasive procedures (e.g., endoscopic ultrasonography) or a selective arterial calcium stimulation test with hepatic venous sampling. Methods: We performed 68Ga-DOTATATE PET/CT on 3 patients with insulinoma. Results: All patients' insulinomas were shown clearly with 68Ga-DOTATATE PET/CT. Conclusion: 68Ga-DOTATATE PET/CT imaging may be a useful noninvasive imaging technique to localize insulinomas preoperatively.