TY - JOUR T1 - Diuretic Renal Scintigraphy in Patients with Sulfonamide Allergies: Possible Alternative Use of Ethacrynic Acid JF - Journal of Nuclear Medicine Technology JO - J. Nucl. Med. Technol. SP - 239 LP - 241 DO - 10.2967/jnmt.115.161331 VL - 43 IS - 4 AU - Ba D. Nguyen AU - Michael C. Roarke AU - Jason Robert Young AU - Ming Yang AU - Howard H. Osborn Y1 - 2015/12/01 UR - http://tech.snmjournals.org/content/43/4/239.abstract N2 - Furosemide may trigger life-threatening sulfonamide cross-hypersensitivity reactions, posing a dilemma in patients who need diuretic renal scintigraphy. Methods: We present our experience using ethacrynic acid as a nonsulfonamide alternative diuretic in 5 patients, with a discussion of the diuretic molecular structure, potential side effects, protocol development, and imaging results. Results: Diuretic renal scintigraphy using ethacrynic acid provided useful information about the obstruction status in all patients, with no adverse clinical impact. Conclusion: Ethacrynic acid is a potential alternative to furosemide for patients with severe sulfonamide reactions. ER -