@article {Nguyen239, author = {Ba D. Nguyen and Michael C. Roarke and Jason Robert Young and Ming Yang and Howard H. Osborn}, title = {Diuretic Renal Scintigraphy in Patients with Sulfonamide Allergies: Possible Alternative Use of Ethacrynic Acid}, volume = {43}, number = {4}, pages = {239--241}, year = {2015}, doi = {10.2967/jnmt.115.161331}, publisher = {Society of Nuclear Medicine}, abstract = {Furosemide may trigger life-threatening sulfonamide cross-hypersensitivity reactions, posing a dilemma in patients who need diuretic renal scintigraphy. Methods: We present our experience using ethacrynic acid as a nonsulfonamide alternative diuretic in 5 patients, with a discussion of the diuretic molecular structure, potential side effects, protocol development, and imaging results. Results: Diuretic renal scintigraphy using ethacrynic acid provided useful information about the obstruction status in all patients, with no adverse clinical impact. Conclusion: Ethacrynic acid is a potential alternative to furosemide for patients with severe sulfonamide reactions.}, issn = {0091-4916}, URL = {https://tech.snmjournals.org/content/43/4/239}, eprint = {https://tech.snmjournals.org/content/43/4/239.full.pdf}, journal = {Journal of Nuclear Medicine Technology} }