PT - JOURNAL ARTICLE AU - LisaAnn Trembath AU - Maureen Newell AU - Michael D. Devous, Sr. TI - Technical Considerations in Brain Amyloid PET Imaging with <sup>18</sup>F-Florbetapir AID - 10.2967/jnmt.115.156679 DP - 2015 Sep 01 TA - Journal of Nuclear Medicine Technology PG - 175--184 VI - 43 IP - 3 4099 - http://tech.snmjournals.org/content/43/3/175.short 4100 - http://tech.snmjournals.org/content/43/3/175.full SO - J. Nucl. Med. Technol.2015 Sep 01; 43 AB - Technical factors play a critical role in the production of best-quality amyloid PET images for interpretation. This article provides specific instructions and general technical information about PET brain scanning of β-amyloid neuritic plaques. The focus of tracer-specific information will be on 18F-florbetapir (indications, contraindications, dosing, administration, uptake time, scanning time, acquisition, processing, biodistribution, radiation dose, adverse events, and display). General scanning information relevant to all amyloid-imaging agents will be also be presented (e.g., mechanism of uptake, safe handling, positioning, prevention of patient motion, processing, and artifacts).