PT  - JOURNAL ARTICLE
AU  - White, A J
AU  - Rachalewska, M
AU  - Venkannagari, R R
TI  - A simple method for measuring severely reduced glomerular filtration rate.
DP  - 2000 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 173--175
VI  - 28
IP  - 3
4099  - http://tech.snmjournals.org/content/28/3/173.short
4100  - http://tech.snmjournals.org/content/28/3/173.full
SO  - J. Nucl. Med. Technol.2000 Sep 01; 28
AB  - The purpose of this study was to develop a simpler method to measure severely reduced glomerular filtration rate (GFR) for patients with a GFR below 30 mL/min.The GFR was measured in 24 patients using both the 51Cr EDTA slope-intercept method (the conventional method) and 99mTc-DTPA with our proposed simpler GFRn method.The correlation coefficient was 0.92 between the 2 methods, with a slope of 0.97 and an intercept of 2 mL/min.Our simplified method for measuring GFR is accurate for most patients with severely reduced GFR. Errors are acceptably small in patients with severely reduced GFR when edema or dehydration are present. If extrarenal (liver) clearance is significant, however, a urine sampling method is required for an accurate GFR measurement.