RT Journal Article
SR Electronic
T1 Experience with Technetium-99m Albumin Colloid Kit for Reticuloendothelial System Imaging
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 149
OP 151
VO 14
IS 3
A1 Saha, Gopal B.
A1 Feiglin, David H.I.
A1 O’Donnell, James K.
A1 Go, Raymundo T.
A1 Karam, Philip M.
A1 MacIntyre, William
YR 1986
UL http://tech.snmjournals.org/content/14/3/149.abstract
AB The 99mTc labeled albumin colloid has been evaluated regarding its particle size, both in vitro and in vivo stability, blood clearance, and efficacy in reticuloendothelial system imaging. The labeling efficiency was always > 99%. The labeled colloid remained stable both in vitro and in vivo for up to 24 hr. The blood clearance curve from four patients had two components: one with a T½ of 2.48 ± 0.37 min and the other with a T½ of 271 ± 109 min. Images of the liver, spleen, and bone marrow with 99mTc-albumin colloid and 99mTc-sulfur colloid showed a similar distribution pattern except that slightly higher splenic uptake relative to the liver was observed with the former. However, 99mTc-albumin colloid has the advantage of easy preparation over 99mTc-sulfur colloid.