@article {Majewski185, author = {Walter Majewski and A. Michael Zimmer and Stewart M. Spies and John Hingeveld}, title = {Radiochemical Evaluation of Commercial Iminodiacetate Hepatobiliary Radiopharmaceuticals}, volume = {9}, number = {4}, pages = {185--187}, year = {1981}, publisher = {Society of Nuclear Medicine}, abstract = {The radiochemical purity of commercially available hepatobiliary iminodiacetate radiopharmaceuticals was evaluated up to 24-hr postformulation. We used a rapid miniaturized chromatography system consisting of Gelman ITLC-SA and 20\% NaCl to evaluate free pertechnetate and Gelman ITLC-SG and distilled water to evaluate hydrolyzed reduced Tc-99m (Tc-HR). Results indicate that minimal radiopharmaceutical breakdown occurred in all IDA agents tested within 5-hr post-formulation. At 8 hr after preparation, some breakdown was observed in specific IDA radiopharmaceuticals as evidenced by increasing pertechnetate levels. Greater radiopharmaceutical instability was observed at 24-hr postformulation. Tc-HR levels remained relatively low (\<5\%) for all IDA agents throughout the study.}, issn = {0091-4916}, URL = {https://tech.snmjournals.org/content/9/4/185}, eprint = {https://tech.snmjournals.org/content/9/4/185.full.pdf}, journal = {Journal of Nuclear Medicine Technology} }