RT Journal Article
SR Electronic
T1 Reproducibility of Technetium-99m Mebrofenin Hepatic Functional Parameters Obtained with Semi-Automatic Software
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 228
OP 231
VO 19
IS 4
A1 Spackman, Jeffry
A1 Bartlett, Marjorie E.
A1 Ryals, LeeAnn
A1 Eklem, Marsha
A1 Gilbert, Susan
A1 Krishnamurthy, Shakuntala
A1 Krishnamurthy, Gerbail T.
YR 1991
UL http://tech.snmjournals.org/content/19/4/228.abstract
AB The reliability of quantitative measurement of two hepatobiliary functional parameters using semi-automatic computer software was tested for reproducibility within and between institutions in an academic and a community hospital. Hepatic extraction fraction (HEF) and excretion half-time (t½) values in ten normal controls and eleven patients were determined independently by two technologists from the same institution and one technologist from a different institution. HEF and excretion t½ values were obtained using semi-automatic nuclear hepatology software and were then compared using the paired t-test to determine their reproducibility. There was no difference in the HEF or excretion t½, values obtained independently by the three technologists. We conclude that results obtained using semi-automatic computer software for quantitative nuclear hepatology with technetium-99m IDA agents are highly reproducible and should be used routinely as a supplement to hepatobiliary imaging studies.