RT Journal Article
SR Electronic
T1 Thallium-201-Chloride Lung Imaging for Bronchogenic Carcinoma
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 83
OP 86
VO 19
IS 2
A1 Wei-Jen Shih
A1 Sylvia Magoun
A1 Vickie Stipp
A1 Kelly Gross
A1 Sara Brandenburg
A1 Becky Wierzbinski
A1 U. Yun Ryo
A1 Marcus Dillon
YR 1991
UL http://tech.snmjournals.org/content/19/2/83.abstract
AB To evaluate the clinical utility of thallium-201-(201Tl) chloride lung imaging for patients with suspected lung tumor or recurrent tumor before and/or after thoracic surgery, 33 men (aged 50 to 79; mean 62) with recurrent or suspected carcinoma of the lung underwent201 Tl-chloride planar lung imaging. Planar lung images (anterior, posterior, and lateral views) were obtained 15 min after i.v. injection of 2–4 mCi of201 Tl-chloride. Thallium-201 lung images were compared with concurrent computed tomography of the chest and correlated to the pathologic results from bronchial washing, bronchoscopic biopsy, lobectomy and/or pneumonectomy. In 23 of 33 patients, planar images were compatible with carcinoma manifesting focal areas of uptake. Ten of the 33 patients had diffuse lung uptake or focal area of lung uptake, while six patients had diffuse or focal uptake of the lung in a nonmalignant condition which interfered with interpretation. Six benign lesions included one in chronic inflammation, one in pneumonia, one in granulomatous inflammation, one in squamous metaplasia, and two in nonmalignancy. Three of the six patients’ lung images showed focal areas of uptake and lung images of three others demonstrated diffuse lung uptake. Diffuse lung uptake in malignant lesions(s) of four patients interfered with scan interpretation. Four of these six patients with nonmalignant conditions and two of four patients with diffuse uptake in malignant lesion(s) had a history of smoking and/or obstructive lung disease, two had undergone recent thoracotomy and one postirradiation. These results suggest201 Tl-chloride localized in the benign lesions of the lung and/or diffuse lung uptake may interfere with the interpretation of201 Tl-chloride lung images.