TY - JOUR T1 - Technetium-99m-HMPAO-labeled leukocyte imaging in patients with seronegative spondyloarthropathies. JF - Journal of Nuclear Medicine Technology JO - J. Nucl. Med. Technol. SP - 204 LP - 206 VL - 27 IS - 3 AU - J C Alonso AU - A Soriano AU - C Rubio AU - J L Cuadra AU - M Zarca AU - P Guerra AU - A Garcia AU - C Molino Y1 - 1999/09/01 UR - http://tech.snmjournals.org/content/27/3/204.abstract N2 - Gut inflammation is frequent among patients with seronegative spondyloarthropathies (SSp). The purpose of this study was to evaluate the presence of positive abdominal findings in patients with SSp who did not have clinical symptoms or signs of inflammatory bowel disease (IBD). This represents a new indication for abdominal 99mTc-HMPAO-labeled leukocyte scintigraphy.Eighty-six patients (59 with SSp and 27 controls) were prospectively imaged with 99mTc-HMPAO-labeled leukocytes.Leukocyte imaging was positive in 33 patients with SSp (56%), 27 of these patients scored between 2+ and 4+ (51%). Four (15%) control patients also had positive findings.These findings provide evidence linking SSp with intestinal inflammation. SSp may be an important new indication for 99mTc-HMPAO-labeled autologous leukocyte scintigraphy. ER -