RT Journal Article
SR Electronic
T1 Technetium-99m-HMPAO-labeled leukocyte imaging in patients with seronegative spondyloarthropathies.
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 204
OP 206
VO 27
IS 3
A1 J C Alonso
A1 A Soriano
A1 C Rubio
A1 J L Cuadra
A1 M Zarca
A1 P Guerra
A1 A Garcia
A1 C Molino
YR 1999
UL http://tech.snmjournals.org/content/27/3/204.abstract
AB Gut inflammation is frequent among patients with seronegative spondyloarthropathies (SSp). The purpose of this study was to evaluate the presence of positive abdominal findings in patients with SSp who did not have clinical symptoms or signs of inflammatory bowel disease (IBD). This represents a new indication for abdominal 99mTc-HMPAO-labeled leukocyte scintigraphy.Eighty-six patients (59 with SSp and 27 controls) were prospectively imaged with 99mTc-HMPAO-labeled leukocytes.Leukocyte imaging was positive in 33 patients with SSp (56%), 27 of these patients scored between 2+ and 4+ (51%). Four (15%) control patients also had positive findings.These findings provide evidence linking SSp with intestinal inflammation. SSp may be an important new indication for 99mTc-HMPAO-labeled autologous leukocyte scintigraphy.