RT Journal Article SR Electronic T1 The Value of Regional Ventilation Measurements in the Prediction of Postoperative Pulmonary Function Following Lobectomy JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 86 OP 88 VO 18 IS 2 A1 LaManna, Margaret M. A1 Rambaran, Naipaul A1 Mezic, Edward T. A1 Murphy, David M. F. A1 Ora-Cajulis, Marivi YR 1990 UL http://tech.snmjournals.org/content/18/2/86.abstract AB Eleven patients, mean age 62, considered for lobectomy for lung carcinoma underwent regional quantitative ventilation/perfusion scintigraphy. Preoperative selection criteria included an FEV1 (forced expiratory volume) of 55% predicted or less, and/or an FEV1/FVC% (forced vital capacity) of <70%. All patients underwent a complete set of pulmonary function tests including flow rates, lung volumes, diffusing capacity and blood gases. A predicted postoperative FEV1 was calculated by multiplying the percent ventilation estimated to be remaining postoperatively by the preoperative FEV1. Results were compared with the actual postoperative FEV1 using a paired t-test. The statistical correlation between the predicted postoperative FEV1 and actual yielded an “r” value of of 0.67 with a “p” value of 0.56. There was good correlation between the predicted postoperative FEV1 utilizing scintigraphy and the actual, but in several cases the predicted postoperative FEV1 was underestimated. Although the degree of underestimation is insignificant, patients may be excluded from lobectomy when their values are marginal.