PT  - JOURNAL ARTICLE
AU  - LaManna, Margaret M.
AU  - Rambaran, Naipaul
AU  - Mezic, Edward T.
AU  - Murphy, David M. F.
AU  - Ora-Cajulis, Marivi
TI  - The Value of Regional Ventilation Measurements in the Prediction of Postoperative Pulmonary Function Following Lobectomy
DP  - 1990 Jun 01
TA  - Journal of Nuclear Medicine Technology
PG  - 86--88
VI  - 18
IP  - 2
4099  - http://tech.snmjournals.org/content/18/2/86.short
4100  - http://tech.snmjournals.org/content/18/2/86.full
SO  - J. Nucl. Med. Technol.1990 Jun 01; 18
AB  - Eleven patients, mean age 62, considered for lobectomy for lung carcinoma underwent regional quantitative ventilation/perfusion scintigraphy. Preoperative selection criteria included an FEV1 (forced expiratory volume) of 55% predicted or less, and/or an FEV1/FVC% (forced vital capacity) of <70%. All patients underwent a complete set of pulmonary function tests including flow rates, lung volumes, diffusing capacity and blood gases. A predicted postoperative FEV1 was calculated by multiplying the percent ventilation estimated to be remaining postoperatively by the preoperative FEV1. Results were compared with the actual postoperative FEV1 using a paired t-test. The statistical correlation between the predicted postoperative FEV1 and actual yielded an “r” value of of 0.67 with a “p” value of 0.56. There was good correlation between the predicted postoperative FEV1 utilizing scintigraphy and the actual, but in several cases the predicted postoperative FEV1 was underestimated. Although the degree of underestimation is insignificant, patients may be excluded from lobectomy when their values are marginal.