RT Journal Article
SR Electronic
T1 Effects of Al<sup>3+</sup> Ion on Tc-99m Sulfur Colloid Preparations with Different Buffers
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 16
OP 18
VO 12
IS 1
A1 Study, K.T.
A1 Hladik, W.B.
A1 Saha, G.B.
YR 1984
UL http://tech.snmjournals.org/content/12/1/16.abstract
AB The effect of aluminum ions on two Tc-99m sulfur colloid preparations, one with phosphate buffer and the other with acetate buffer, was studied by the filtration technique using Nuclepore filters of sizes 0.6 μm, 3 μm, and 10 μm. The aluminum concentrations were &lt; 0.5, 7.5, and 15 μg/ml of the final preparation. A considerable number of large particles (3-10 μm) formed in the sulfur colloid preparation containing phosphate buffer when the Al3+ concentration was 7.5 μg/ml or more. This particle formation was not observed with sulfur colloid preparation containing acetate buffer.