PT - JOURNAL ARTICLE AU - Study, K.T. AU - Hladik, W.B. AU - Saha, G.B. TI - Effects of Al<sup>3+</sup> Ion on Tc-99m Sulfur Colloid Preparations with Different Buffers DP - 1984 Mar 01 TA - Journal of Nuclear Medicine Technology PG - 16--18 VI - 12 IP - 1 4099 - http://tech.snmjournals.org/content/12/1/16.short 4100 - http://tech.snmjournals.org/content/12/1/16.full SO - J. Nucl. Med. Technol.1984 Mar 01; 12 AB - The effect of aluminum ions on two Tc-99m sulfur colloid preparations, one with phosphate buffer and the other with acetate buffer, was studied by the filtration technique using Nuclepore filters of sizes 0.6 μm, 3 μm, and 10 μm. The aluminum concentrations were &lt; 0.5, 7.5, and 15 μg/ml of the final preparation. A considerable number of large particles (3-10 μm) formed in the sulfur colloid preparation containing phosphate buffer when the Al3+ concentration was 7.5 μg/ml or more. This particle formation was not observed with sulfur colloid preparation containing acetate buffer.