RT Journal Article
SR Electronic
T1 Common Errors Associated with Miniaturized Chromatography
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 66
OP 68
VO 11
IS 2
A1 Webber, Denise
A1 Zimmer, A.M.
A1 Spies, Stewart M.
YR 1983
UL http://tech.snmjournals.org/content/11/2/66.abstract
AB Miniaturized chromatography systems have been used over the years with few problems; yet it is imperative that a standard procedure be scrupulously followed. Variation in proper radiochromatographic technique can result in false radiopurity estimations. The two most frequent causes of these errors are simple procedural mistakes: (1) counting the strips too close to the gamma scintillation detector, thus exceeding count rate capabilities; and (2) spotting the origin below the initial solvent level in developing vials. Improper technique can result in large overestimations of impurity levels in Tc-99m-labeled radiopharmaceuticals.