RT Journal Article
SR Electronic
T1 Study of Transit Time Measurement with a Lung Test Object
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 20
OP 23
VO 21
IS 1
A1 Chen, Ching Y.
A1 Youngblood, Douglas
A1 Chu, Robert Y. L.
YR 1993
UL http://tech.snmjournals.org/content/21/1/20.abstract
AB We studied the radioactive indicator-dilution technique with a lung test object. A bolus of technetium-99m pertechnetate was injected repeatedly. The input time-activity curves were fitted by biexponential or gamma-variate functions; the output time-activity curves were described by gamma-variate functions. The mean transit time was calculated with the fitted modeling functions for input and output. Transit times were also obtained directly from the experimental data with the replacement of region of recirculation by extrapolation from the modeling function. The reproducibility of transit time measurement by the radioactive tracer technique was determined to be ±0.2 sec. We found no significant difference between the use of modeling function and the direct use of experimental data.