PT  - JOURNAL ARTICLE
AU  - Maguire, William J.
TI  - Deadtime Error with Iodine-123 Thyroid Uptake Measurements
DP  - 1988 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 105--108
VI  - 16
IP  - 3
4099  - http://tech.snmjournals.org/content/16/3/105.short
4100  - http://tech.snmjournals.org/content/16/3/105.full
SO  - J. Nucl. Med. Technol.1988 Sep 01; 16
AB  - Thyroid uptake measurements performed using iodine-123 (123I) are subject to a systemic error due to deadtime loss when the standard is derived based on a decay factor. Higher deadtime loss with 123I is due to using more activity along with its better detection efficiency, higher count rate, and shorter half-life compared to that of 131I. The degree of error due to deadtime loss may range from insignificant to extreme, depending on a number of factors. Degree of error is related to the activity administered, the window settings, the age and energy resolution of the instrumentation, and the elapsed time between standard and patient counts.