RT Journal Article
SR Electronic
T1 Dispensing Therapeutic Amounts of Holmium-166 with a Radionuclide Calibrator
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 275
OP 278
VO 23
IS 4
A1 Diaz, M.
A1 Macey, D. J.
A1 Kasi, L. P.
A1 Bayouth, J.E.
A1 Podoloff, D.A.
YR 1995
UL http://tech.snmjournals.org/content/23/4/275.abstract
AB Objective: A high-purity germanium detector (HPGe) spectrometry system was used to calibrate a radionuclide calibrator for the accurate dispensing of therapeutic amounts of 166Ho to be administered to patients. Methods: A calibrated 60Co source was counted simultaneously in the same geometry as the 166Ho for acquisition of gamma ray spectra. The sensitivity of the HPGe detector for the 1.379-MeV photons emitted by 166Ho was determined from the 1.333-MeV photons emitted from 60Co. This measured amount of 166Ho was placed in an assay calibrator and the sensitivity control adjusted so that the readout matched the 166Ho content. Results: The dial setting required for the Capintec CRC-15R was found to be 748 times 10. Conclusion: This assay of 166Ho with a HPGe detector has proved useful for adjusting the sensitivity of a clinical radionuclide calibrator and can be extended to provide calibration factors for other assay calibrators used to dispense therapeutic amounts of other radionuclides used for clinical nuclear medicine procedures.