RT Journal Article
SR Electronic
T1 Is It Possible to Avoid Standards in Studies With Blood Samples?
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 271
OP 274
VO 23
IS 4
A1 Mrhac, Luban
A1 Zakko, Saad
A1 Salih, Omaima
YR 1995
UL http://tech.snmjournals.org/content/23/4/271.abstract
AB Objective: The long-term mutual stability of a tandem radionuclide calibrator-well detector was measured to enable us to omit reference standards in the estimation of blood volume and GFR/ERPF and thus simplify the procedures, and potentially make the results more precise. Methods: During two months 200 measurements of reference standard aliquots were taken to estimate the stability of a factor of mutual relation (FMR), which provides a conversion constant between a radionuclide calibrator reading and count rate of a diluted aliquot measured in a well detector. Results: All measurements demonstrated the satisfactory mutual stability of the detectors. Conclusion: An FMR can be used instead of making up standard aliquots. The activity in the syringe is measured directly in a radionuclide calibrator before injection. The value is then multiplied by the FMR and the result is used in the equation for blood volume or GFR calculation.