PT  - JOURNAL ARTICLE
AU  - Mrhac, Luban
AU  - Zakko, Saad
AU  - Salih, Omaima
TI  - Is It Possible to Avoid Standards in Studies With Blood Samples?
DP  - 1995 Dec 01
TA  - Journal of Nuclear Medicine Technology
PG  - 271--274
VI  - 23
IP  - 4
4099  - http://tech.snmjournals.org/content/23/4/271.short
4100  - http://tech.snmjournals.org/content/23/4/271.full
SO  - J. Nucl. Med. Technol.1995 Dec 01; 23
AB  - Objective: The long-term mutual stability of a tandem radionuclide calibrator-well detector was measured to enable us to omit reference standards in the estimation of blood volume and GFR/ERPF and thus simplify the procedures, and potentially make the results more precise. Methods: During two months 200 measurements of reference standard aliquots were taken to estimate the stability of a factor of mutual relation (FMR), which provides a conversion constant between a radionuclide calibrator reading and count rate of a diluted aliquot measured in a well detector. Results: All measurements demonstrated the satisfactory mutual stability of the detectors. Conclusion: An FMR can be used instead of making up standard aliquots. The activity in the syringe is measured directly in a radionuclide calibrator before injection. The value is then multiplied by the FMR and the result is used in the equation for blood volume or GFR calculation.