RT Journal Article SR Electronic T1 Use of a Single-Strip Chromatography System to Assess the Lipophilic Component in Technetium-99m Exametazime Preparations JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 29 OP 32 VO 20 IS 1 A1 Webber, Denise I. A1 Zimmer, A. Michael A1 Geyer, Monica C. A1 Spies, Stewart M. YR 1992 UL http://tech.snmjournals.org/content/20/1/29.abstract AB Use of a single-strip miniaturized chromatography system to quantitate the lipophilic component in technetium-99m (99mTc) exametazime preparations was investigated. The chromatography system consisted of Whatman 17 strips and ethyl acetate as the solvent system. The operation parameters, accuracy and reliability of the single-strip chromatography system, were evaluated. Results of the study demonstrated that the single-strip chromatography system was accurate in assessing the lipophilic fraction in 99mTc exametazime preparations when compared to the three-strip chromatography method. The single strip system is rapid with a solvent developing time of ~2 min. As outlined, the single-strip chromatography system can easily be incorporated into the radiopharmaceutical quality control program of any nuclear medicine department.