PT  - JOURNAL ARTICLE
AU  - Webber, Denise I.
AU  - Zimmer, A. Michael
AU  - Geyer, Monica C.
AU  - Spies, Stewart M.
TI  - Use of a Single-Strip Chromatography System to Assess the Lipophilic Component in Technetium-99m Exametazime Preparations
DP  - 1992 Mar 01
TA  - Journal of Nuclear Medicine Technology
PG  - 29--32
VI  - 20
IP  - 1
4099  - http://tech.snmjournals.org/content/20/1/29.short
4100  - http://tech.snmjournals.org/content/20/1/29.full
SO  - J. Nucl. Med. Technol.1992 Mar 01; 20
AB  - Use of a single-strip miniaturized chromatography system to quantitate the lipophilic component in technetium-99m (99mTc) exametazime preparations was investigated. The chromatography system consisted of Whatman 17 strips and ethyl acetate as the solvent system. The operation parameters, accuracy and reliability of the single-strip chromatography system, were evaluated. Results of the study demonstrated that the single-strip chromatography system was accurate in assessing the lipophilic fraction in 99mTc exametazime preparations when compared to the three-strip chromatography method. The single strip system is rapid with a solvent developing time of ~2 min. As outlined, the single-strip chromatography system can easily be incorporated into the radiopharmaceutical quality control program of any nuclear medicine department.