RT Journal Article
SR Electronic
T1 Indium-111 Platelet Labeling Using Homologous Platelets
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 222
OP 224
VO 22
IS 4
A1 Colloms, Charles
A1 Cheng, Kenneth T.
A1 Haymond, Dave
YR 1994
UL http://tech.snmjournals.org/content/22/4/222.abstract
AB Objective: This paper describes an 111In-labeled platelet procedure using substituted donor platelets (homologous) in acutely thrombocytopenic patients. Methods: In two patients, we used packed donor platelets which were centrifuged once. Once the platelets were isolated, they were incubated with 111In-oxine in an anticoagulated solution of normal saline for 5 min. Upon resuspension in the plasma, the platelets were injected into the patients who were imaged with a dual-headed SPECT camera the following day. Results: We successfully labeled packed donor platelets to produce clinically acceptable images by modifying the current standard protocol for platelet labeling. Conclusion: Indium-111 platelet labeling of donor platelets is a feasible alternative to autologous labeling in acutely thrombocytopenic patients.