PT - JOURNAL ARTICLE AU - Charles Colloms AU - Kenneth T. Cheng AU - Dave Haymond TI - Indium-111 Platelet Labeling Using Homologous Platelets DP - 1994 Dec 01 TA - Journal of Nuclear Medicine Technology PG - 222--224 VI - 22 IP - 4 4099 - http://tech.snmjournals.org/content/22/4/222.short 4100 - http://tech.snmjournals.org/content/22/4/222.full SO - J. Nucl. Med. Technol.1994 Dec 01; 22 AB - Objective: This paper describes an 111In-labeled platelet procedure using substituted donor platelets (homologous) in acutely thrombocytopenic patients. Methods: In two patients, we used packed donor platelets which were centrifuged once. Once the platelets were isolated, they were incubated with 111In-oxine in an anticoagulated solution of normal saline for 5 min. Upon resuspension in the plasma, the platelets were injected into the patients who were imaged with a dual-headed SPECT camera the following day. Results: We successfully labeled packed donor platelets to produce clinically acceptable images by modifying the current standard protocol for platelet labeling. Conclusion: Indium-111 platelet labeling of donor platelets is a feasible alternative to autologous labeling in acutely thrombocytopenic patients.