PT  - JOURNAL ARTICLE
AU  - Romanelli-Beardsley, Michelle A.
AU  - Moldofsky, Philip J.
AU  - Mulhern, Charles B.
TI  - Tumor Imaging with I-131 Labeled F(ab’)<sub>2</sub> Fragments of Monoclonal Antibodies
DP  - 1983 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 113--114
VI  - 11
IP  - 3
4099  - http://tech.snmjournals.org/content/11/3/113.short
4100  - http://tech.snmjournals.org/content/11/3/113.full
SO  - J. Nucl. Med. Technol.1983 Sep 01; 11
AB  - Using radiolabeled F(ab’)2 fragments of monoclonal antibody associated with a noncirculating cell surface antigen of colon carcinoma, we have demonstrated preferential localization in small deposits of human colon carcinoma. (Images show tumor deposition without background subtraction.) Biologic distribution of the F(ab’)2 fragments is also evaluated. In 16 patients studied to date, tumor deposits as small as 1.5 cm have been readily visualized on unprocessed images without background subtraction. Optimal imaging time (tumors best defined) is 72-96 hr postadministration.