RT Journal Article
SR Electronic
T1 A Three-Parameter Statistical System for Radioimmunoassay Quality Control
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 115
OP 118
VO 11
IS 3
A1 Sarno, Sara G.
YR 1983
UL http://tech.snmjournals.org/content/11/3/115.abstract
AB We have implemented an efficient system of radioimmunoassay quality control using three statistical parameters: a Z-score plot for each control pool, a Z-sum plot that combines the Z-scores, and an average of normals graph. Concrete criteria were established for evaluation of assay validity. Use of these three parameters allows differentiation between random and systematic errors, detection of control sera biodegradation, and information as to sources of systematic errors. The system also allows increased reliability of results, fewer repeat assays, and rapid problem recognition and solution with a negligible increase in time spent on quality control procedures.