RT Journal Article
SR Electronic
T1 Mean Transit Time: Proof and Esophageal Example
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP 5
OP 8
VO 16
IS 1
A1 Klein, Herbert A.
YR 1988
UL http://tech.snmjournals.org/content/16/1/5.abstract
AB The transit of radioactive tracers in human systems provides information of physiologic and diagnostic importance. A simple, nontechnical proof is offered for the formula for computation of mean transit time as area/height of a time-activity curve. It is specifically applicable to esophageal transit, and may also serve to illuminate other uses in nuclear medicine. The alternative centroid formula for mean transit time differs in meaning but is compatible with the area/height formula. Considerations regarding mean transit time suggest ways to determine the attenuation of radioactivity that affects a compartment under study.