PT  - JOURNAL ARTICLE
AU  - English, Robert J.
AU  - Jones, Alun G.
AU  - Davison, Alan
AU  - Lister-James, John
AU  - Campbell, Stephen
AU  - Holman, B. Leonard
TI  - Imaging Considerations for a Technetium-99m Myocardial Perfusion Agent
DP  - 1986 Mar 01
TA  - Journal of Nuclear Medicine Technology
PG  - 6--10
VI  - 14
IP  - 1
4099  - http://tech.snmjournals.org/content/14/1/6.short
4100  - http://tech.snmjournals.org/content/14/1/6.full
SO  - J. Nucl. Med. Technol.1986 Mar 01; 14
AB  - Myocardial perfusion imaging with 201 Tl chloride suffers from a number of physical, geometric, and dosimetric constraints that could be diminished if an agent labeled with 99mTc were available. The cationic complex 99mTc hexakis-(t-butylisonitrile)technetium(I) ([99mTc]TBI) has been shown to concentrate in the myocardial tissue of both animals and humans, with preliminary clinical studies demonstrating a number of technical attributes not possible with 201 Tl. Technetium-99m-TBI is a promising myocardial imaging agent that may permit high quality planar, gated, and tomographic imaging of both myocardial ischemia and infarction with reduced imaging times and improved resolution.