PT  - JOURNAL ARTICLE
AU  - Richards, Paul A.C.
TI  - Thyroid Stimulating Hormone Immunoassay Using Heel Prick Plasma for Follow-Up Screening of Neonates to Confirm Hypothyroidism
DP  - 1979 Dec 01
TA  - Journal of Nuclear Medicine Technology
PG  - 230--232
VI  - 7
IP  - 4
4099  - http://tech.snmjournals.org/content/7/4/230.short
4100  - http://tech.snmjournals.org/content/7/4/230.full
SO  - J. Nucl. Med. Technol.1979 Dec 01; 7
AB  - A rapid, sensitive radioimmunoassay for TSH is described that requires a whole blood specimen collected by heel prick using an EDTA microhematocrit capillary tube. The technique was adapted from a commercially available kit and allows for hematocrit determination to correct day five T4 spot screening and low plasma volume assaying (10 μl). The collection procedure is atraumatic to the newborn when compared with the difficulties of venous sampling. This method is also advantageous for small volume venous samples and should be useful for follow-up on recalled newborns for positive diagnosis of neonatal hypothyroidism.