RT Journal Article SR Electronic T1 Sequential Brain and Bone Imaging with 99m Tc-Diphosphonate JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 76 OP 79 VO 4 IS 2 A1 Earl L. Gaston YR 1976 UL http://tech.snmjournals.org/content/4/2/76.abstract AB Both brain and bone imaging are often required in evaluating patients with suspected metastatic disease. This usually necessitates a delay of one to two days between the studies since 99mTc is routinely used in both procedures. This article describes a possible method of eliminating this time delay by utilizing 99mTc-diphosphonate as a sequential brain- and bone-imaging radiopharmaceutical. The results indicate that detection of intracranial lesions with 99mTc-diphosphonate compares favorably with pertechnetate cerebral imaging in the studies presented and it may be a suitable agent for sequential brain and bone imaging.