PT - JOURNAL ARTICLE AU - Earl L. Gaston TI - Sequential Brain and Bone Imaging with <sup>99m</sup> Tc-Diphosphonate DP - 1976 Jun 01 TA - Journal of Nuclear Medicine Technology PG - 76--79 VI - 4 IP - 2 4099 - http://tech.snmjournals.org/content/4/2/76.short 4100 - http://tech.snmjournals.org/content/4/2/76.full SO - J. Nucl. Med. Technol.1976 Jun 01; 4 AB - Both brain and bone imaging are often required in evaluating patients with suspected metastatic disease. This usually necessitates a delay of one to two days between the studies since 99mTc is routinely used in both procedures. This article describes a possible method of eliminating this time delay by utilizing 99mTc-diphosphonate as a sequential brain- and bone-imaging radiopharmaceutical. The results indicate that detection of intracranial lesions with 99mTc-diphosphonate compares favorably with pertechnetate cerebral imaging in the studies presented and it may be a suitable agent for sequential brain and bone imaging.